Happiness2.0 Lab aims to offer science-based communication activities to 14-to-18-year-old adolescents living in Ticino, parents, and stakeholders. We will discuss how social media use influences adolescents’ well-being over time, considering positive well-being indicators (e.g., happiness) and developmental processes like personality formation and the need for social connections. Happiness2.0 includes two weeks of a 2-hour laboratory, “HappyLab” that combines science and arts. That will be followed by HappyApero activities, during which teens will engage with experts, parents, and adults. Finally, during the HappyTable, stakeholders, teachers, and high school principals will be invited to reflect on the activity of 2024 and launch the Happiness2.0 for 2025.